Jesus is confident that the church’s mission will succeed because the church is animated by the Holy Spirit, and Jesus can completely trust the work of the Spirit in and through the church.
We [the church] are invited to participate in an activity of God which is the central meaning of creation itself. We are invited to become, through the presence of the Holy Spirit, participants in the Son’s loving obedience to the Father. All things have been created that they may be summed up in Christ the Son. All history is directed towards that end.
A brilliant talk on Spirit-Empowered Mission
If Christianity can be expressed in all languages and cultures, then it is also true that it doesn’t belong to any particular language or culture. No one can say that they own the Christian faith.
It would be easy – very easy – for a Western rationalist to dismiss all of this. I’m a biologist, I know what causes diseases!
There are a number of conclusions that you can draw from these incidents; but the idea that the Holy Spirit always guides in a clear and unambiguous fashion is not one of them!